Role of 16-S RNA in Ribosome Messenger Recognition
نویسندگان
چکیده
منابع مشابه
Ribosome-bound messenger RNA in T4-infected bacteria.
The olassieal experiments of Hall, Nygaard & Green (1964) established the following facts concerning messenger RNA synthesis in Escherichia wli B infected with bacteriophage T2: most of the RNA species present early in the latent period (before phage DNA synthesis begins) are still present after the DNA synthetic rate is maximal (late period); radioactive precursors administered to infected cel...
متن کاملThe hydrodynamic and spectroscopic properties of 16 S RNA from Escherichia coli ribosome in reconstitution buffer.
The hydrodynamic shape, conformation, and thermal stability of ribosomal16 S RNA in reconstitution buffer have been studied by sedimentation velocity, intrinsic viscosity, circular dichroism, and difference ultraviolet absorption spectroscopy. These results are compared with the corresponding properties of the 30 S ribosomal subunit in order to understand the role of the RNA molecule in the ass...
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The radioactively labelled product of RNA-dependent RNA polymerase+ from ribosomes of immature chicken erythrocytes was tested for the presence of newly replicated globin mRNA using unlabelled globin complementary DNA. No radioactively labelled globin mRNA sequences were found in the product, providing direct confirmation that this RNA-dependent RNA polymerase is not involved in globin mRNA amp...
متن کاملThe Path of Messenger RNA through the Ribosome
Using X-ray crystallography, we have directly observed the path of mRNA in the 70S ribosome in Fourier difference maps at 7 A resolution. About 30 nucleotides of the mRNA are wrapped in a groove that encircles the neck of the 30S subunit. The Shine-Dalgarno helix is bound in a large cleft between the head and the back of the platform. At the interface, only about eight nucleotides (-1 to +7), c...
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Models of mRNA translation usually presume that transcripts are linear; upon reaching the end of a transcript each terminating ribosome returns to the cytoplasmic pool before initiating anew on a different transcript. A consequence of linear models is that faster translation of a given mRNA is unlikely to generate more of the encoded protein, particularly at low ribosome availability. Recent ev...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1980
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1980.tb04904.x